Research Assistantship in Clincial Proteomics - Rajarhat, Kolkata, West Bengal, India - Tata Medical Center
Description
Research Assistantship(RA) at the TTCRC Clinical Proteomics Unit
Appointing Organisation
Tata Translational Cancer Research Centre
Tata Medical Center, Kolkata
**Last Date of Application:16/09/2023
The Tata Medical Center and the Tata Translational Cancer Research Centre
The Tata Medical Center (TMC) is a multispecialty institution for tertiary cancer care based in
New Town, Kolkata. At TMC, clinical and research activities are integrated to provide state-of
- the-art care for patients with cancer. This integration is enabled in the Tata Translational Cancer
Research Centre (TTCRC), the research arm of TMC. TTCRC is within a dedicated academic
space and spread over 3 floors. At TTCRC, a multidisciplinary team of clinicians, scientists,
academics, and industry professionals collaborate to develop a systems medicine approach in
cancer research. This approach is focussed on developing innovative, indigenous, cost-effective
and equitable strategies to improve cancer diagnosis; develop treatments that match disease
characteristics and are adapted to treatment response; and, identify prognostic and predictive
disease biomarkers. These strategies are multi-dimensional and involve an iterative pathway that
include clinical studies, high-throughput laboratory investigations, computational strategies to
integrate, analyse and model data, hypothesis-based pre-clinical studies and evidence-based
translation of findings to clinical practice.
The opportunity at TTCRC Clinical Proteomics Unit
We offer a Research Assistantship position to train you on handling liquid chromatography
coupled to mass-spectrometry (LC-MS/MS) instrument. In this position you will work as part of
the proteomics team at TTCRC. The group's work is focussed currently on two aspects, 1.
developing plasma proteomics and biomarker discovery platform in both solid cancer and
Leukaemia. 2. providing proteomics solutions to other in-house clinical research teams where you
is supported by a dedicated tissue biorepository, a clinical research unit, genomics and informatics
analyses. Access to resources include confocal microscopy, flow cytometry, dedicated tissue
culture facility, virus transduction facility and mass spectroscopy. Your primary responsibility will
be understanding the working of the Clinical Proteomics Unit. It'll include troubleshooting,
optimizing and maintaining the working of the LC-MS/MS instrument; as well as developing,
testing and standardizing various sample preparation and purification techniques. It'll be a regular
activity to aid other groups in their requirements for processing samples through the proteomic
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pipeline and as well in supporting with the data analysis. You'll be expected to understand the
biology of the drug mechanisms in cellular environment.
Minimum required qualifications/experience
MSc/M. Tech in Biological Sciences, including Life Sciences, Genetic Engineering,
Biotechnology, Cell & Molecular Biology, and Microbiology.
Hands-on experience with molecular biology techniques like Protein purification, Gel
Electrophoresis, Western Blotting, etc.
Desirable Experience:
Prior experience (1-2 years) in Proteomics/ Protein extraction,
purification, Gel electrophoresis, Liquid Chromatography like HPLC, FPLC etc.
Prior exposure to LC-MS/MS system is preferred but not mandatory
Familiarity with basic theory of Mass-Spectrometry and Protein Biology is essential.
Necessary qualities
(a) Integrity, motivation, enthusiasm
(b) Focus and commitment in carrying out tasks and duties
(c) Critical analytical and problem-solving skills, capable of independent work
(d) Ability to work effectively as part of a multidisciplinary team
(e) Clarity in career and professional development goals
Appointment and reporting
to satisfactory review of performance at the end of the tenure. The monthly remuneration would be
according to the TTCRC policy. The successful applicant will be managed by the Team Lead,
Clinical Proteomics Unit and will report to the Director, TTCRC.
Enquiries
Mr Suvasish Mukherjee; Head, Human Resources; Tata Medical Center; 14 Major Arterial
Road (East-West); Newtown, Rajarhat; Kolkata
(c) For informal enquiries,
1) Dr. Trina Dutta, Post-Doctoral Fellow, Clinical Proteomics Unit, TTCRC-TMC.
2) Mr. Satadru Dey, Administrative Assistant, TTCRC-TMC.
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