beBee background
Professionals
>
Pune
Anirudh Murali

Anirudh Murali

Space Biology, Computational Biology

Pharmaceutical / Bio-tech

Pune, Pune

Social


About Anirudh Murali:

I'm currently pursuing my Doctoral research under the mentorship of Dr. Ram Rup Sarkar at CSIR - National Chemical Laboratory, India. My work focuses on elucidating the impact of microgravity on immune cell behaviour by integrating fluid dynamics simulations, network-based systems biology, and mathematical modelling through differential equations.

🔬 Research Focus & Technical Expertise
✔️ Computational Immunology – Modelling immune cell adaptation under biophysical stressors such as altered gravity
✔️ Systems Biology & Network Analysis – Leveraging TRRUST, REACTOME, and STRING to map and analyse protein interaction networks
✔️ Particle- and Fluid-Based Simulations – Developing DPD-based models to explore fluid–cell and solid–fluid interactions
✔️ Data Analysis & Statistical Modelling – Applying R and Python for omics data interpretation and functional annotation

My research aims to bridge physics-driven simulations with biological interpretation, offering a multiscale perspective on how gravity influences immune regulation. I am particularly interested in simulating complex cellular environments using Python-based particle interaction frameworks.
I welcome discussions and collaborations in computational biology, biophysical modelling, and systems immunology. Let’s connect!

#ComputationalBiology #SystemsImmunology #MicrogravityResearch #Biophysics #NetworkBiology

Experience

  • Mesoscale CFD modelling of biofluid and RBC dynamics under altered gravity: Developed and validated a 2D mesoscale CFD (DPD) model to analyse biofluid and Red Blood Cell (RBC) dynamics under altered gravity (0g- 2g), quantifying mechanical metrics and the impact of hydrodynamic/gravitational forces on RBC morphology and distribution.
  • Characterisation of WBC dynamic responses in microgravity environments: Developed a 2D mesoscale DPD model of White Blood Cells (WBCs) to predict and characterise morphological adaptations and mechanical force interactions (shear, drag) under altered gravity, with comparative RBC analysis.
  • Modelling cyto-nuclear architectural adaptations in WBCs to gravitational variations: Advanced WBC model to include nuclear/cytoskeletal structures, investigating intracellular force transmission and characterising cyto-nuclear morphological deformations in response to altered gravity and fluid stresses.
  • Development of computational pipeline for integrating mechanotransduction in T-cells: An integrated computational pipeline combining CFD force data with a Signal Flow Algorithm (SFA) to quantify gravitational effects on T-cell protein expression and signal propagation; validated against transcriptomic datasets.

Education

Ph.D. in Engineering Sciences (Integrated Dual-Degree Ph.D.) CSIR- National Chemical Laboratory, Pune

Professionals in the same Pharmaceutical / Bio-tech sector as Anirudh Murali

Professionals from different sectors near Pune, Pune

Other users who are called Anirudh

Jobs near Pune, Pune

  • Work in company

    Deep Research Annotator

    Deccan AI Experts

    We are looking for highly skilled Biology / Life Sciences experts to work as Deep Research Annotators on advanced annotation and RLHF projects. · Review and annotate biology and life sciences research content for RLHF and AI training datasets · ,Evaluate scientific reasoning, hyp ...

    Pune, Maharashtra

    1 month ago

  • Work in company

    Senior Analyst, Pricing Analytics

    Johnson & Johnson MedTech

    We are seeking a highly motivated Senior Analyst, Pricing Analytics to join our team of analytics experts in the Commercial Excellence team at J&J Vision. · Build and maintain pricing analytics capabilities for monthly and quarterly performance of key pricing metrics, profitabili ...

    Pune, Maharashtra

    1 month ago

  • Work in company

    Teacher

    Dhruv Global School

    We are looking for a passionate and dedicated School Teacher to join our academic team. The ideal candidate will be responsible for delivering engaging lessons. · ...

    Pune

    1 month ago